共查询到20条相似文献,搜索用时 156 毫秒
1.
田基黄(口山)酮成分的研究 总被引:2,自引:0,他引:2
采用萃取,硅胶及凝胶柱色谱等方法从田基黄全草中分离得到了7个San酮类化合物,利用UV、IR、^1H NMR、^13C NMR、MS等波谱技术将他们的结构分别鉴定为6-脱氧异巴西红厚壳素(1)、异巴西红厚壳素(2)、1,3,5,6-四羟基San酮(3)、1,3,6,7-四羟基San酮(4),1,3,5,6-四羟基-4-异戊烯San酮(5)、1,3,5-三羟基San酮(6)和bijaponicaxanthone(7),其中化合物3、4和6为首次从该植物中分得的San酮类化合物。 相似文献
2.
用反相HPLC内标定量方法测定18-甲基-3-甲氧基-8,14-开裂雌甾-1,3,5(10),9(11)-四烯-14,17-二酮微生物不对称还原成具有光学活性17β-羟基化合物的转化率。色谱采用μ-BondapakC14色谱柱;甲醇-水73∶27(V/V)为流动相,流量0.8 ml/min;UV 254 nm检测;雄甾-4-烯-3,17-二酮作内标。 相似文献
3.
为研究柯拉斯那(Aquilaria crassna Pierre ex Lecomte)沉香的化学成分。实验采用多种柱色谱方法从该沉香中分离得到9个2-(2-苯乙基)色酮类化合物,通过现代波谱学技术分别鉴定为6-甲氧基-2-[2-(3′-羟基-4′-甲氧基苯基)乙基]色酮(1)、5-羟基-6-甲氧基-2-[2-(3′-羟基-4′-甲氧基苯基)乙基]色酮(2)、tetrahydrochromone F(3)、6-甲氧基-2-[2-(3′-甲氧基-4′-羟基苯基)乙基]色酮(4)、6-甲氧基-7-羟基-2-[2-(4′-甲氧基苯基)乙基]色酮(5)、6,7-二甲氧基-2-[2-(3′-羟基-4′-甲氧基苯基)乙基]色酮(6)、6,7-二甲氧基-2-[2-(4′-甲氧基苯基)乙基]色酮(7)、6-羟基-2-[2-(4′-羟基苯基)乙基]色酮(8)、5-羟基-2-[2-(2′-羟基苯基)乙基]色酮(9)。化合物2、3和5~9均为首次从柯拉斯那所得沉香中分离得到。采用MTT法对单体化合物的细胞毒活性进行测试,测试结果表明,化合物1,2和4具有微弱的细胞毒活性。 相似文献
4.
白木香果实化学成分研究 总被引:2,自引:2,他引:0
运用柱色谱技术从白木香(Aquilaria sinensis (Lour.) Gilg)果实中分离得到7个化合物,经波谱解析和理化性质分别鉴定为: 3-吲哚甲酸(1)、6-羟基-2-[2-(4-羟基苯基)乙基]色原酮(2)、芫花素(3)、4', 5-二羟基-3',7-二甲氧基黄酮(4)、洋芹素-7,4'-二甲醚(5)、 β-谷甾醇(6)和胡萝卜苷(7)。其中化合物1为首次从瑞香科沉香属植物中分离得到。 相似文献
5.
海南灵芝化学成分研究 总被引:1,自引:0,他引:1
为探讨海南灵芝(Ganoderma hainanense Zhao,Xu et Zhang)的化学成分,采用柱层析技术从海南灵芝乙醇提取物中分离得到14个化合物。经波谱分析鉴定其结构分别为:巴西红厚壳素(1)、6-脱氧巴西红厚壳素(2)、7,8-二甲基咯嗪(3)、5,8-过氧麦角固醇(4)、3β,5α,9α-三羟基麦角甾-7,22-二烯-6-酮(5)、麦角甾-7,22-二烯-3β-醇(6)、麦角甾-7,22-二烯-3-酮(7)、7α-甲氧基-5α,6α-环氧麦角甾-8(14),22-二烯-3β-醇(8)、麦角甾-7,22-二烯-3β,5α-6β-三醇(9)、3-吲哚甲酸(10)、3,4-二羟基苯甲酸(11)、对羟基苯甲酸(12)、3,4-二羟基苯甲酸甲酯(13)和正二十六烷酸(14)。所有化合物均为首次从海南灵芝中分离得到。 相似文献
6.
从陆地革菌(Thelephora terrestris)子实体中分离得到9个已知化合物,经波谱学分析鉴定为:(22E,24R)-麦角甾-7,22-二烯-3β -醇 (1),(22E, 24R)-麦角甾-7, 22-二烯-3β ,5α,6β -三醇 (2),(22E,24R)-麦角甾-4,6,8(14),22-四烯-3-酮 (3),24-亚甲基羊毛甾-8-烯-3β -醇 (4),熊果酸 (5),木栓酮 (6),cerebroside B (7),(2S,3S,4R,2'R)-2-(2'-羟基二十二碳酰氨基)-十八碳烷-1,3,4-三醇 (8),(2S,3S,4R,2'R)-2-(2'-羟基二十三碳酰氨基)-十八碳烷-1,3,4-三醇 (9)。 相似文献
7.
8.
9.
碳源和氮源对水母雪莲悬浮培养细胞生长和黄酮合成的影响 总被引:10,自引:0,他引:10
在MS培养基上进行水母雪莲(Saussurea medusa Maxim)细胞悬浮培养时研究了碳源和氮源的影响。结果表明碳源以蔗糖最适合,蔗糖浓度则以40g/L较好,细胞生长量干重为18.12g/L,总黄酮合成量达到1423.25mg/L。在培养过程中,水母雪莲细胞能够快速将蔗糖水解为葡萄糖和果糖,并首先利用葡萄糖。氮源总浓度(包括NH+4和NO-3)为60~120mmol/L,NH+4/NO-3比例为20/40有利于雪莲细胞生长和黄酮合成。用HPLC检测显示4′,5,7-三羟基3′,6-二甲氧基黄酮(Jaceosidin)和4′,5,7-三羟基-6-甲氧基黄酮(Hispidulin)2种黄酮的含量分别达到细胞干重的1.46%和0.010% 相似文献
10.
从川西獐牙菜(Swcrtia mussotii Franch)中分离和鉴定了八种咄酮成分,即1,8-二羟基-3,5-二甲氧基(口山)酮Ⅰ,1-羟基-3,5-二甲氧基(口山)酮Ⅱ,1-羟基-3,7,8-三甲氧基咄酮Ⅲ,8-羟基-1,3,5-二甲氧基(口山)酮Ⅳ,1,8-二羟基-3,7-二甲氧基(口山)酮Ⅴ,1,7,8-三羟基-3-甲氧基咄酮Ⅵ,1,7-二羟基-3,4,8-三甲氧基(口山)酮Ⅶ和1,3,8-三羟基-5-甲氧基(口山)酮Ⅷ。其中,1,7-二羟基-3,4,8-三甲氧基(口山)酮为新的天然化合物,命名为藏茵陈(口山)酮(zangyinchenin)。 相似文献
11.
Six xanthones, 1,3,7-trihydroxy-2-(2-hydroxy-3-methyl-3-butenyl)-xanthone (1), 1,7-dihydroxy-2,3-[2'-(1-hydroxy-1-methylethyl)-dihydrofurano]-xanthone (2), 1,3,7-trihydroxy-5-methoxyxanthone (3), 1,7-dihydroxy-5,6-dimethoxyxanthone (4), 4,5-dihydroxy-2,3-dimethoxyxanthone (5), 1,3-dihydroxy-2,4-dimethoxyxanthone (6) and 21 known xanthones were isolated from the leaves and stems of Hypericum chinense. Their structures were established based on spectroscopic studies. 相似文献
12.
Cho N Huh J Yang H Jeong EJ Kim YC Kim J Sung SH 《Journal of enzyme inhibition and medicinal chemistry》2012,27(1):1-4
A methanolic extract of the roots of Polygala tenuifolia (Polygalaceae) significantly attenuated nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglia cells. Five xanthones, 1-hydroxy-7-methoxyxanthone (1), 3,6-dihydroxy-1,2,7-trimethoxyxanthone (2), 1,3,6-trihydroxy-2,7-dimethoxyxanthone (3), 1,7-dihydroxy-2,3-dimethoxyxanthone (4) and 1,7-dihydroxy-3-methoxyxanthone (5), and five phenylpropanoids, 4-hydroxy-3-methoxypropiophenone (6), methyl 4-hydroxy-3-methoxycinnamic acid (7), 3,4,5-trimethoxycinnamic acid (8), 4-methoxycinnamic acid (9) and β-d-(3-O-sinapoyl) fructofuranosyl-α-d-(6-O-sinapoyl)glucopyranoside (10), were isolated from CHCl(3) fraction using bioactivity-guided fractionation. Among these compounds, compounds 1, 2, 4, 5 and 7 showed significant inhibitory effects on LPS-induced NO production in BV2 microglia cells at the concentration ranging from 10.0 to 100.0 μM. 相似文献
13.
Antônio A. Lins Mesquita Wanderley Gonçlves De Oliveira Rosa M. Taveira Neiva Otto R. Gottlieb 《Phytochemistry》1975,14(3):803-806
The wood of Tovomita pyrifolium (Guttiferae) contains the novel tovopyrifolins A [1,6-dihydroxy-7-methoxy-5-prenyl-6′,6′-dimethylpyrano (2′,3′:3,2)xanthone], B (1,5-dihydroxy-3,4-dimethoxyxanthone) and C (1,3,5-trihydroxy-2-methoxyxanthone) and also the known tovophyllins A and B [structure revised to 1,6-dihydroxy-5-prenyl-6′, 6′-dimethylpyrano(2′,3′:3,2)-6″,6″-dimethylpyrano(2″,3″:7,8)xanthone]. 相似文献
14.
Swertia erythrosticta Maxim. (Gentianaceae) is a herb used for curing some diseases in Tibetan traditional medicine system. Eight xanthones were isolated from this species. Their structures were identified as 1,8-dihydroxy-3,7-dimethoxyxanthone(Ⅰ), 1,5,8-trihydroxy-3-methoxyxanthone (Ⅱ), 1,3,8-trihydroxy-5-methoxyxanthone (Ⅲ), 1,7,8-trihydroxy-3-methoxyxanthone (Ⅳ), 1,3,5,8-tetrahydroxyxanthone (Ⅴ), 1,3,7,8-tetrahydroxyxanthone(Ⅵ), as well as 8-O-β-D-glucopyranosyl-1, 5-dihydroxy-3 -metho xy xanthone(Ⅶ), 8-O-β-D-gl ucopyr anosyl- 1,3,5- trihydroxyxanthone(Ⅷ) by means of chemical methodes and spectral analyses. 相似文献
15.
A new polyisoprenylated benzophenone, guttiferone I, together with the known compounds cambogin, 1,7-dihydroxyxanthone, 1,3,6,7-tetrahydroxyxanthone and 1,3,5,6-tetrahydroxyxanthone were isolated from the stem bark of Garcinia griffithii. The acetone extract of the heartwood of Garcinia mangostana contained one new diprenylated xanthone (mangoxanthone) and a new benzophenone (3',6-dihydroxy-2,4,4'-trimethoxybenzophenone) as well as the known xanthones dulxanthone D, 1,3,7-trihydroxy-2-methoxyxanthone, 1,3,5-trihydroxy-13,13-dimethyl-2H-pyran[7,6-b]xanthen-9-one. Their structures were established on the basis of spectroscopic studies and chemical correlation. 相似文献
16.
Dall'Acqua S Viola G Cappelletti EM Innocenti G 《Zeitschrift für Naturforschung. C, Journal of biosciences》2004,59(5-6):335-338
Bioactivity-guided fractionation of Polygala alpestris L. (Rchb.) extracts led to the identification of two new xanthones, 1,3,7-trihydroxy-2,6-dimethoxyxanthone (1) and 2,3-methylenedioxy-4,7-dihydroxyxanthone (2). In addition five known compounds 3,4-dimethoxy-1,7-dihydroxyxanthone (3), 1,3-dihydroxy-7-methoxyxanthone (4), 1,7-dihydroxy-2,3-dimethoxyxanthone (5), 3',6-O-disinapoyl sucrose (6) and 3',5'-dimethoxybiphenyl-4-olo (7) were isolated. The structures of the isolated compounds were established by means of high resolution mass spectrometry, mono- and bi-dimensional NMR spectroscopy. All isolated compounds were tested for cytotoxic activity against three tumor cell lines (LoVo, HL-60, K 562). 相似文献
17.
Nine compounds were isolated from Gentianopsis barbata var. stennocalyx H. W. Li ex. T.N.Ho. Their structures are identified as 1-hydroxy4, 7, 8-trimethoxyxanthone (Ⅰ), 1, 7-dihydroxy-3, 8-dimethoxyxanthone (Ⅱ), 1, 7, 8-trihydroxy-3-methoxyxanthone (Ⅲ), 1-O-(β-D- xylopyranosyl-(1→6)-β-D-glucopyranosyl)-3, 7, 8-trimethoxyxanthone (Ⅳ), 1-O-(β-D-xylopy- ranosyl- (1→6)-β-D-glucopyranosyl)-7-hydroxy-3, 8-dimethoxyxanthone (Ⅴ), 1-O-(β-D-xylo- pyranosyl-(1→6)-β-D-glucopyranosyl)-7, 8-dihydroxy-3-methoxyxanthone (Ⅵ), luteolin-7-O- β-D-glucoside (Ⅶ), oleanolic acid (Ⅷ) and ursolic acid (Ⅸ) by means of chemical methods and UV, IR and NMR determinations respectively. 相似文献
18.
Seven xanthonenoid compounds and a triterpenic acid have been isolated from Swertia przewalskii Pissjauk. Their structures were identified as 1,8-dihydroxy-3,7-dimethoxyxarthone(Ⅰ), 1,7-dihydroxy-3,8-dimethoxyxanthone (Ⅱ), oleanolic acid (Ⅲ), l-hydroxy-3,7,8-trimethoxyxanthone (Ⅳ), 1,7,8-trihydroxy-3-methoxyxanthone (Ⅴ), 8-0-[β-D-xylopyranosyl-(l--6)-β-D-glucopyranosyl]- 1,7-dihydr0xy- 3-methoxyxanthone (Ⅵ), 1-O- [β-D-xylopyranosyl-(1-6)-β-D-glucopyranosyl]-7,8-dihydroxy- 3-methoxyxanthone (Ⅶ) and 1-O- [β-D-xylopyranosyl-(1-6)-β-D-glucopyranosyl]-8-hydroxy-3,7-dimethoxyanthone (Ⅷ) respectively, by means of chemical and spectral methods or comparing with the authentic samples directly. 相似文献
19.
Vijaya Kumar Subramaniam Sotheeswaran Sivagnanasundram Surendrakumar Sinnathamby Balasubramaniam 《Phytochemistry》1982,21(3):807-809
The bark of Calophyllum calaba var. calaba contains a new xanthone, 2,8-di-(3-methylbut-2-enyl)-1,3-dihydroxy-7-methoxyxanthone (calocalabaxanthone), the precursor of 5-hydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-2H,6H-pyano-(3,2-b)-xanthen-6-one (calabaxanthone). In addition the bark contains calabaxthone and the other constituents isolated earlier from Calophyllum calaba var. worthingtonii. 相似文献
20.
Xanthones from Calophyllum teysmannii var. inophylloide 总被引:1,自引:0,他引:1
Further study of the wood of Calophyllum teysmannii Miq. var. inophylloide yielded xanthones 7-hydroxy-1,2,8-trimethoxyxanthone, 6-hydroxy-1,2,5-trimethoxyxanthone, and 2-carbomethoxy-6-methoxyxanthone in addition to 3,8-dihydroxy-1,2,4-trimethoxyxanthone, 3-hydroxy-2,4-dimethoxyxanthone, 1,7-dihydroxy-3-methoxyanthone (gentisin) and 2-hydroxyxanthone. 相似文献