共查询到20条相似文献,搜索用时 390 毫秒
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Enhancer-facilitated expression of a human H4 histone gene 总被引:2,自引:0,他引:2
A Shiels F Marashi G Stein J Stein 《Biochemical and biophysical research communications》1985,127(1):239-246
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Human U2 small nuclear RNA genes contain an upstream enhancer. 总被引:41,自引:11,他引:30
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The Epstein-Barr virus (EBV) early promoter DR contains a cis-acting element responsive to the EBV transactivator EB1 and an enhancer with constitutive and inducible activities. 总被引:19,自引:15,他引:4 下载免费PDF全文
P Chavrier H Gruffat A Chevallier-Greco M Buisson A Sergeant 《Journal of virology》1989,63(2):607-614
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A J van Wijnen K L Wright J B Lian J L Stein G S Stein 《The Journal of biological chemistry》1989,264(25):15034-15042
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Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene. 总被引:66,自引:41,他引:25 下载免费PDF全文
E A Sternberg G Spizz W M Perry D Vizard T Weil E N Olson 《Molecular and cellular biology》1988,8(7):2896-2909
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Transcription of the chicken histone H5 gene is mediated by distinct tissue-specific elements within the promoter and the 3'' enhancer. 总被引:2,自引:0,他引:2 下载免费PDF全文
Molecular genetic analysis of a number of vertebrate erythroid cell-specific genes has identified at least two types of cis-acting regulatory sequences which control the complex developmental pattern of gene expression during erythroid cell maturation. Tissue-specific cellular enhancers have been identified 3' to three erythroid cell-specific genes, and additional regulatory elements have been identified in the promoters of many erythroid genes. We show that the histone H5 enhancer, like the adult beta-globin enhancer, is involved in mediating the developmental induction of histone H5 mRNA as erythroid cells mature. We also describe the preliminary characterization of a tissue-specific regulatory element within the 5' region of the H5 locus and describe investigations of the interaction between this element and the histone H5 enhancer in mediating histone H5 regulation. 相似文献