共查询到20条相似文献,搜索用时 31 毫秒
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Inhibition of Cyclin D1 Kinase Activity Is Associated with E2F-Mediated Inhibition of Cyclin D1 Promoter Activity through E2F and Sp1 总被引:19,自引:10,他引:9 下载免费PDF全文
Genichi Watanabe Chris Albanese Richard J. Lee Anne Reutens Gino Vairo Berthold Henglein Richard G. Pestell 《Molecular and cellular biology》1998,18(6):3212-3222
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Francesco Fabris Andrea Sgarro Alessandro Tossi 《EURASIP Journal on Bioinformatics and Systems Biology》2007,2007(1):31450
Mathematical tools developed in the context of Shannon information theory were used to analyze the meaning of the BLOSUM score, which was split into three components termed as the BLOSUM spectrum (or BLOSpectrum). These relate respectively to the sequence convergence (the stochastic similarity of the two protein sequences), to the background frequency divergence (typicality of the amino acid probability distribution in each sequence), and to the target frequency divergence (compliance of the amino acid variations between the two sequences to the protein model implicit in the BLOCKS database). This treatment sharpens the protein sequence comparison, providing a rationale for the biological significance of the obtained score, and helps to identify weakly related sequences. Moreover, the BLOSpectrum can guide the choice of the most appropriate scoring matrix, tailoring it to the evolutionary divergence associated with the two sequences, or indicate if a compositionally adjusted matrix could perform better.[1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29] 相似文献
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Novel Regulatory Factors Interacting with the Promoter of the Gene Encoding the mRNA Cap Binding Protein (eIF4E) and Their Function in Growth Regulation 总被引:1,自引:0,他引:1 下载免费PDF全文
Kelly A. Johnston Michael Polymenis Shanping Wang John Branda Emmett V. Schmidt 《Molecular and cellular biology》1998,18(10):5621-5633
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Human T-Cell Leukemia Virus Type 1 Tax Protein Abrogates Interleukin-2 Dependence in a Mouse T-Cell Line 总被引:5,自引:3,他引:2 下载免费PDF全文
Youichi Iwanaga Tomonori Tsukahara Takashi Ohashi Yuetsu Tanaka Masaaki Arai Masataka Nakamura Kiyoshi Ohtani Yoshihiro Koya Mari Kannagi Naoki Yamamoto Masahiro Fujii 《Journal of virology》1999,73(2):1271-1277
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Stimulation of Cyclin-Dependent Kinase Activity and G1- to S-Phase Transition in Human Lymphocytes by the Human T-Cell Leukemia/Lymphotropic Virus Type 1 Tax Protein 总被引:4,自引:0,他引:4 下载免费PDF全文
Iris Schmitt Oliver Rosin Peter Rohwer Manfred Gossen Ralph Grassmann 《Journal of virology》1998,72(1):633-640
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