Supply and demand: Cellular nutrient uptake and exchange in cancer

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Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia

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NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

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MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”

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A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior

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Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2

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Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter

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Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state

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Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression

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Functional Translatome Proteomics Reveal Converging and Dose-Dependent Regulation by mTORC1 and eIF2α

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Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models

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In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

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Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals

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Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

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Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus

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Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition

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Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway

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Chromatin-bound RB targets promoters,enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression

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TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration

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GSK3 and lamellipodin balance lamellipodial protrusions and focal adhesion maturation in mouse neural crest migration

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