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Modulation of WHSC2 expression in human endothelial cells 总被引:2,自引:0,他引:2
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Differential utilization of calcitonin gene regulatory DNA sequences in cultured lines of medullary thyroid carcinoma and small-cell lung carcinoma. 总被引:3,自引:1,他引:2 下载免费PDF全文
A de Bustros R Y Lee D Compton T Y Tsong S B Baylin B D Nelkin 《Molecular and cellular biology》1990,10(4):1773-1778
Regulation of expression of the human calcitonin gene was found to differ between two tumor lines of different tissue origin, medullary thyroid carcinoma (TT line) and small-cell lung carcinoma (DMS53 line). Distal 5' DNA elements between -750 and -2000 exhibited a stronger basal activity in DMS53 than in TT cells, whereas proximal DNA sequences between -132 and -252 mediated a dramatic cyclic AMP response in TT but not DMS53 cells. 相似文献
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Sugimoto H Sugimoto S Tatei K Obinata H Bakovic M Izumi T Vance DE 《The Journal of biological chemistry》2003,278(22):19716-19722
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