Supppression of paradoxical sleep by chloramphenicol. Absence of effect by thiamphenicol]

The oral administration of 160-250 mg/kg of chloramphenicol selectively suppresses Paradoxical Sleep in the cat for a duration of 10-20 hours. Larger doses (330 mg/kg) suppress Paradoxical Sleep for 27 hours, but aslso decrease Slow Wave Sleep. At the same dose, Thiamphenicol has no effect.     

Sleep and epilepsy

Sleep and Biological Rhythms - This review article aims to describe the strong association between sleep and epilepsy. Sleep disturbance or sleep disorders are frequently observed comorbid...     

Undergraduate dental education on oral appliance therapy for obstructive sleep apnea at The University of British Columbia

Sleep and Biological Rhythms - The updated practice parameters from the American Academy of Sleep Medicine in 2006 have concluded that oral appliances are indicated for mild to moderate obstructive...     

Disordered sleep and its association with academic performance and functioning

Sleep and Biological Rhythms - Sleep disorders are prevalent among college students and are associated with poor academic performance. Few studies have included a clinical interview to...     

Sleep disturbances and risk of sick leave: systematic review and meta-analysis

Sleep and Biological Rhythms - Sleep disturbances have multiple negative effects on psychological, social, and occupational aspects. The effects of sleep disturbances on the risk of taking sick...     

Physiological and autonomic stress responses after prolonged sleep restriction and subsequent recovery sleep in healthy young men

Sleep and Biological Rhythms - Sleep restriction is increasingly common and associated with the development of health problems. We investigated how the neuroendocrine stress systems respond to...     

Activation of phasic pontine-wave generator: A mechanism for sleep-dependent memory processing

Sleep and Biological Rhythms - Sleep and learning studies suggest that memory consolidation following learning requires processes selectively active during rapid eye movement (REM) sleep. However,...     

Validation of the Pittsburgh Sleep Quality Index (PSQI) with Arabic cancer patients

Sleep and Biological Rhythms - The Pittsburgh Sleep Quality Index (PSQI), a self-administrated questionnaire, is a frequently used instrument to assess sleep quality in clinical and non-clinical...     

Sleep spindle characteristics in overweight adolescents with obstructive sleep apnea syndrome

Sleep and Biological Rhythms - Sleep spindles may display a sleep protective function. Thus, their activity is also a stable marker of sleep disturbances. We investigated whether spindle activity...     

Relationship between nutrition and sleep quality,focusing on the melatonin biosynthesis

Sleep and Biological Rhythms - Sleep duration and quality are associated with many diseases. Evaluating the relationship between nutrient intake and sleep quality is important, because dietary...     

Heterogeneity of sleep quality based on the Pittsburgh Sleep Quality Index in a community sample: a latent class analysis

Sleep and Biological Rhythms - This study aims to assess the latent dimensional structure of sleep quality as measured by seven components of the Pittsburgh Sleep Quality Index (PSQI) and evaluate...     

Prevalence of sleep disorders in the Turkish adult population epidemiology of sleep study

Sleep and Biological Rhythms - Sleep disorders constitute an important public health problem. Prevalence of sleep disorders in Turkish adult population was investigated in a nationwide...     

The association of brain lesion locations and sleep parameters in patients with multiple sclerosis: a pilot study

Sleep and Biological Rhythms - The relationship between sleep and brain lesions remains unknown in patients with multiple sclerosis (MS) and is currently under investigation. Sleep deprivation and...     

Sleep patterns and sleep problems in a sample of Spanish schoolchildren

Sleep and Biological Rhythms - Sleep in children is essential for growth, emotional health and cognitive function. Although it has been described that poor sleep can seriously affect learning...     

A reliability and validity study of the Bergen Shift Work Sleep Questionnaire in nurses working three-shift rotations

The "Bergen Shift Work Sleep Questionnaire" (BSWSQ) was developed to systematically assess discrete sleep problems related to different work shifts (day, evening, night shifts) and rest days. In this study, we assessed the psychometric properties of the BSWSQ using a sample of 760 nurses, all working in a three-shift rotation schedule: day, evening, and night shifts. BSWSQ measures insomnia symptoms using seven questions: >30-min sleep onset latency, >30-min wake after sleep onset, >30-min premature awakenings, nonrestorative sleep, being tired/sleepy at work, during free time on work days, and when not working/on vacation. Symptoms are assessed separately for each work shift and rest days, as "never," "rarely," "sometimes," "often," "always," or "not applicable." We investigated the BSWSQ model fit, reliability (test-retest of a subsample, n = 234), and convergent and discriminant validity between the BSWSQ and Epworth Sleepiness Scale, Fatigue Questionnaire, and Hospital Anxiety Depression Scale. We also investigated differences in mean scores between the different insomnia symptoms with respect to different work shifts and rest days. BSWSQ demonstrated an adequate model fit using structural equation modeling: root mean square error of approximation =?.071 (90% confidence interval [CI]?=?.066-.076), comparative fit index =?.91, and chi-square/degrees of freedom = 4.41. The BSWSQ demonstrated good reliability (test-retest coefficients p < .001). We found good convergent and discriminant validity between BSWSQ and the other scales (all coefficients p < .001). There were significant differences between the overall/composite scores of the various work shifts. Night shift showed the highest score compared to day and evening shifts as well as to rest days (all post hoc comparisons p < .001). Mean scores of different symptoms also varied significantly within the individual work shifts. We conclude that the BSWSQ meets the necessary psychometric standards, enabling systematic study of discrete insomnia symptoms in different work shifts.     

Prevalence and associations of insomnia in lung transplant recipients

Sleep and Biological Rhythms - The burden of comorbidities post-lung transplant is well documented; however, there remains a paucity of studies on insomnia in this population. Sleep disturbance has...     

Sleep deprivation suppresses adult neurogenesis: Clues to the role of sleep in brain plasticity

Sleep and Biological Rhythms - Sleep is hypothesized to play a critical role in facilitating brain growth and plasticity. Neurogenesis in the adult hippocampus is a recently established model of...     

An Australasian Commentary on the AASM Manual for the Scoring of Sleep and Associated Events

Sleep and Biological Rhythms - The aim of this document was to provide a commentary on the AASM Manual for Scoring of Sleep and Associated Events in an Australasian context. A panel of Australasian...     

Sex differences in subjective sleep quality,sleepiness, and health-related quality of life among collegiate soccer players

Sleep and Biological Rhythms - Sleep is an important recovery phase after exercise that should be taken into account by athletes. Females are likely to be dissatisfied with their sleep quality,...     

Latency of auditory P300 response is related with cognitive deficits in Obstructive Sleep Apnea Syndrome

Sleep and Biological Rhythms - Obstructive Sleep Apnea Syndrome (OSAS) is characterized by desaturation in blood oxygen level and sleep fragmentation because of repeated upper airway obstruction....