Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease

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Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting

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Monoallelic pathogenic ALG5 variants cause atypical polycystic kidney disease and interstitial fibrosis

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Periodontal disease is associated with increased gut colonization of pathogenic Haemophilus parainfluenzae in patients with Crohn’s disease

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Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19

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Multi-omics reveal microbial determinants impacting responses to biologic therapies in inflammatory bowel disease

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Immunoglobulin A Targets a Unique Subset of the Microbiota in Inflammatory Bowel Disease

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The global burden of metabolic disease: Data from 2000 to 2019

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Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures

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Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases

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A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery

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From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease

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The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability

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Propionic Acid Promotes the Virulent Phenotype of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli

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Reshaping endoplasmic reticulum quality control through the unfolded protein response

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Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk

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Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy

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The AD tau core spontaneously self-assembles and recruits full-length tau to filaments

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Conformational change of α-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson’s disease

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Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

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