A Review of: “RECEPTOR BIOCHEMISTRY AEiD METHODOLOGY,J.C. Venter & L.C. Harrison,Eds. Alan R. Liss,New York, 1964, hardbound; Vol.1: 238 pages, $46.00; V01.2: 306 pages, $52.00; Vo1.3: 184 pages, $34.00”

Abstract

Prothrombin complex (P.C.) preparations obtained by batch adsorption onto DEAE-Sephadex are highly enriched in C4. Based on this observation a technique has been elaborated where the P.C. analogue is further submitted to precipitation by ethanol and batch adsorption of impurities on DEAE-Cellulose. Unaltered C4 is obtained in a 2 days process with a yield corresponding to 40 % of the starting material (cryoconcentrate supernatant).