PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

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H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ

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BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation

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Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK

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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

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SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt

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TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation

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TRPS1 drives heterochromatic origin refiring and cancer genome evolution

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TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

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The Regulatory Proteins Rtg1/3 Govern Sphingolipid Homeostasis in the Human-Associated Yeast Candida albicans

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RIPK1 Promotes Energy Sensing by the mTORC1 Pathway

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Shank3 Binds to and Stabilizes the Active Form of Rap1 and HRas GTPases via Its NTD-ANK Tandem with Distinct Mechanisms

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Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A

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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling

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TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis

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LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes

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Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3

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Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling

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STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina

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