共查询到20条相似文献,搜索用时 15 毫秒
1.
2.
Cordelia Bolle Gunnar Huep Nils Kleinbölting Georg Haberer Klaus Mayer Dario Leister Bernd Weisshaar 《The Plant journal : for cell and molecular biology》2013,75(1):157-171
Owing to duplication events in its progenitor, more than 90% of the genes in the Arabidopsis thaliana genome are members of multigene families. A set of 2108 gene families, each consisting of precisely two unlinked paralogous genes, was identified in the nuclear genome of A. thaliana on the basis of sequence similarity. A systematic method for the creation of double knock‐out lines for such gene pairs, designated as DUPLO lines, was established and 200 lines are now publicly available. Their initial phenotypic characterisation led to the identification of seven lines with defects that emerge only in the adult stage. A further six lines display seedling lethality and 23 lines were lethal before germination. Another 14 lines are known to show phenotypes under non‐standard conditions or at the molecular level. Knock‐out of gene pairs with very similar coding sequences or expression profiles is more likely to produce a mutant phenotype than inactivation of gene pairs with dissimilar profiles or sequences. High coding sequence similarity and highly similar expression profiles are only weakly correlated, implying that promoter and coding regions of these gene pairs display different degrees of diversification. 相似文献
3.
4.
5.
Kieffer M Master V Waites R Davies B 《The Plant journal : for cell and molecular biology》2011,68(1):147-158
6.
Lai-Sheng Meng Xu-Dong Sun Fei Li Hai-Liang Liu Zhen-Hua Feng Jian Zhu 《Acta Physiologiae Plantarum》2010,32(2):315-324
7.
8.
9.
10.
11.
12.
J. Serrano-Cartagena P. Robles M. R. Ponce J. L. Micol 《Molecular & general genetics : MGG》1999,261(4-5):725-739
Although a vast inventory of morphological mutants of Arabidopsis thaliana is available, only some have been used for genetic studies of leaf development. Such is the case with the Arabidopsis Information Service (AIS) Form Mutants collection, assembled by A. R. Kranz and currently stored at the Nottingham Arabidopsis Stock Centre, which includes a large number of mutant lines, most of which have been little studied. With the aim of contributing
to the genetic dissection of leaf ontogeny, we have subjected 57 mutant lines isolated by others to genetic analysis; 47 of
which were from the AIS collection. These are characterized by vegetative leaves of abnormal shape or size, and were chosen
as candidates for mutations in genes required for leaf morphogenesis. The mutant phenotypes studied were shown to be inherited
as single recessive Mendelian traits and were classified into 10 phenotypic classes. These mutant strains were found to fall
into 37 complementation groups, 7 of which corresponded to known genes. Results of the phenotypic analysis and data on the
genetic interactions of these mutants are presented, and their possible developmental defects discussed.
Received: 28 October 1998 / Accepted: 21 February 1999 相似文献
13.
14.
15.
Molecular adaptation in the world's deepest‐living animal: Insights from transcriptome sequencing of the hadal amphipod Hirondellea gigas 下载免费PDF全文
Renmao Tian Douglas H. Bartlett Runsheng Li Yue Him Wong Weipeng Zhang Jian‐Wen Qiu Ting Xu Li‐Sheng He Harry G. Tabata Pei‐Yuan Qian 《Molecular ecology》2017,26(14):3732-3743
16.
17.
18.