Chromosome Markers in MUS MUSCULUS: Strain Differences in C-Banding |
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| Authors: | V G Dev D A Miller and O J Miller |
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| Affiliation: | Departments of Human Genetics and Development and of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, N.Y. 10032 |
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| Abstract: | The mitotic chromosomes of several inbred strains of mice and a series of F(1) hybrids have been analyzed by quinacrine staining and further characterized by the centromeric heterochromatin banding (C-banding). Inbred strains had the same amount of C-banding material on homologous chromosomes but showed variation in the amount on different chromosomes. F(1) hybrids showed characteristics of each parent and it appears that the amount of C-banding on each chromosome is a simple inherited polymorphism. In this study 12 different chromosomes could be distinguished by their C-banding, and these can be used as normal chromosome markers. |
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