Tunable excitation properties of ZnCdS:Mn/ZnS quantum dots for cancer imaging |
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| Authors: | Naiqiang Yin Ling Liu Peng Li Shihua Zhao |
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| Affiliation: | 1. School of Physics and Electrical Information, Shangqiu Normal University, Shangqiu, People's Republic of China;2. College of Science, Tianjin Polytechnic University, Tianjin, People's Republic of China |
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| Abstract: | Water‐soluble ZnS:Mn quantum dots (QDs) were synthesized using a hydrothermal method with 3‐mercaptopropionic acid as stabilizer. The optical properties of ZnS:Mn QDs were thoroughly investigated by tuning the doping concentration of Mn2+ and the Zn/S precursor ratio, to obtain an optimal parameter for QDs with excellent fluorescence characteristics. ZnS:Mn QDs excited at only one wavelength, however, which seriously limited their further application. Here, a trace Cd ion was doped into a ZnS host, resulting in QD excitation covering a wide adjustable waveband. Furthermore, when a ZnS shell was coated onto the surface of the ZnCdS:Mn QDs, photoluminescence intensity and stability were further enhanced. After coupling with an anti‐CK 19 antibody, the ZnCdS:Mn/ZnS core/shell QDs were able to function by labeling cancer cells, indicating that they could be considered as a suitable bio‐probe for cells and tissue imaging. |
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| Keywords: | fluorescence quantum dots semiconductors |
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