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Xanthomonas campestris pv. campestris possesses a single gluconeogenic pathway that is required for virulence
Authors:Tang Dong-Jie  He Yong-Qiang  Feng Jia-Xun  He Bao-Ren  Jiang Bo-Le  Lu Guang-Tao  Chen Baoshan  Tang Ji-Liang
Affiliation:College of Life Science and Technology, Guangxi University, 100 Daxue Road, Nanning, Guangxi 530004, People's Republic of China.
Abstract:Disruption of ppsA, a key gene in gluconeogenesis, of Xanthomonas campestris pv. campestris resulted in the failure of the pathogen to grow in medium with pyruvate or C4-dicarboxylates as the sole carbon source and a significant reduction in virulence, indicating that X. campestris pv. campestris possesses only the malic enzyme-PpsA route in gluconeogenesis, which is required for virulence.
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