MAL11 and MAL61 encode the inducible high-affinity maltose transporter of Saccharomyces cerevisiae. |
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| Authors: | Q Cheng and C A Michels |
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| Affiliation: | Department of Biology, Queens College, CUNY, Flushing 11367. |
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| Abstract: | We have investigated the transport of maltose in a genetically defined maltose-fermenting strain of Saccharomyces cerevisiae carrying the MAL1 locus. Two kinetically different systems were identified: a high-affinity transporter with a Km of 4 mM and a low-affinity transporter with a Km of 70 to 80 mM. The high-affinity maltose transporter is maltose inducible and is encoded by the MAL11 (and/or MAL61) gene of the MAL1 (and/or MAL6) locus. The low-affinity maltose transporter is expressed constitutively and is not related to MAL11 and/or MAL61. Both maltose transporters are subject to glucose-induced inactivation. |
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