Chemical Composition and Antimicrobial Activity of the Essential Oil of Ruta chalepensis L. Growing Wild in Lebanon |
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| Authors: | Madona Khoury Didier Stien Naïm Ouaini Véronique Eparvier Nelly Arnold?Apostolides Marc El?Beyrouthy |
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| Affiliation: | 1. CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 1 Avenue de la Terrasse, F‐91198 Gif‐sur‐Yvette (phone: +33‐1‐69823610;2. fax: +33‐1‐69823784);3. Department of Agricultural Sciences, Holy Spirit University of Kaslik, Kaslik, B.P. 446, Jounieh, Lebanon |
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| Abstract: | The essential oils (EOs) isolated from the fresh aerial parts of Ruta chalepensis L. collected in North Lebanon were obtained by solvent‐free microwave extraction (Milestone®), yielding 0.12% EO from both the leaves and a mixture of stems and leaves. The EOs were characterized by GC/MS analysis, and 27 components were identified, which were primarily ketones (88.0–93.2%). The main components were nonan‐2‐one and undecan‐2‐one. The antimicrobial activity of the EOs against a Gram‐positive and a Gram‐negative bacterium, a yeast, and a dermatophyte was evaluated using the broth‐microdilution technique and expressed as minimal inhibitory concentration (MIC). The EOs revealed moderate in vitro antifungal activity against Trichophyton rubrum and Candida albicans. |
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| Keywords: | Ruta chalepensis Essential oils Antimicrobial activity Undecan‐2‐one Nonan‐2‐one |
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