Codon usage patterns in Nematoda: analysis based on over 25 million codons in thirty-two species |
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| Authors: | Makedonka Mitreva Michael C Wendl John Martin Todd Wylie Yong Yin Allan Larson John Parkinson Robert H Waterston James P McCarter |
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| Affiliation: | (1) Genome Sequencing Center, Washington University School of Medicine, St Louis, Missouri 63108, USA;(2) Department of Biology, Washington University, St. Louis, Missouri 63130, USA;(3) Hospital for Sick Children, Toronto, and Departments of Biochemistry/Medical Genetics and Microbiology, University of Toronto, M5G 1X8, Canada;(4) Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA;(5) Divergence Inc., St Louis, Missouri 63141, USA |
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| Abstract: | Background Codon usage has direct utility in molecular characterization of species and is also a marker for molecular evolution. To understand
codon usage within the diverse phylum Nematoda, we analyzed a total of 265,494 expressed sequence tags (ESTs) from 30 nematode
species. The full genomes of Caenorhabditis elegans and C. briggsae were also examined. A total of 25,871,325 codons were analyzed and a comprehensive codon usage table for all species was
generated. This is the first codon usage table available for 24 of these organisms. |
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