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Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline
Authors:Giuseppe Lupo  Paola S Nisi  Pilar Esteve  Yu‐Lee Paul  Clara Lopes Novo  Ben Sidders  Muhammad A Khan  Stefano Biagioni  Hai‐Kun Liu  Paola Bovolenta  Emanuele Cacci  Peter J Rugg‐Gunn
Affiliation:1. Department of Chemistry, Sapienza University of Rome, Rome, Italy;2. Department of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Rome, Italy;3. Centro de Biologia Molecular “Severo Ochoa”, Consejo Superior de Investigaciones Cientificas‐Universidad Autonoma de Madrid, Madrid, Spain;4. CIBER of Rare Diseases, ISCIII, Madrid, Spain;5. Epigenetics Programme, The Babraham Institute, Cambridge, UK;6. Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK;7. Division of Molecular Neurogenetics, German Cancer Research Centre (DKFZ), DKFZ‐ZMBH Alliance, Heidelberg, Germany;8. Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK
Abstract:
Keywords:DNA methylation  epigenetics  histone methylation  neural stem/progenitor cells  neurospheres  subventricular zone
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