Murine protein which binds preferentially to oligo-C-rich single-stranded nucleic acids. |
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Authors: | M Goller B Funke C Gehe-Becker B Krger F Lottspeich and I Horak |
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Affiliation: | M Goller, B Funke, C Gehe-Becker, B Kröger, F Lottspeich, and I Horak |
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Abstract: | Two single-stranded nucleic acid binding proteins mCBP and mCTBP were identified by means of their binding to a potential recombination hotspot in LTRs of mouse retro-transposons. Both are nuclear proteins of 35 and 55 kDa respectively. mCBP binds preferentially to oligo dC, mCTBP to oligo dCdT. mCBP was purified and its cDNA was isolated and sequenced. |
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