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Energy metabolism of bloodstream form Trypanosoma theileri |
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| Authors: | van Hellemond Jaap J Hoek Aad Wichgers Schreur Paul Chupin Vladimir Ozdirekcan Suat Geysen Dirk van Grinsven Koen W A Koets Ad P Van den Bossche Peter Geerts Stanny Tielens Aloysius G M |
| Affiliation: | Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80176, 3508 TD Utrecht, The Netherlands. |
| Abstract: | Bloodstream form Trypanosoma theileri degrades glucose to acetate (47%) and succinate (45%) and, therefore, does not solely rely on glycolysis for ATP production. This trypanosomatid does not use amino acids for energy metabolism. These results refute the prevailing hypothesis that substrate availability determines the type of energy metabolism of trypanosomatids. |
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