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Endothelial STAT3 Activation Increases Vascular Leakage Through Downregulating Tight Junction Proteins: Implications for Diabetic Retinopathy
Authors:Jang‐Hyuk Yun  Sung Wook Park  Kyung‐Jin Kim  Jong‐Sup Bae  Eun Hui Lee  Sun Ha Paek  Seung U Kim  Sangkyu Ye  Jeong‐Hun Kim  Chung‐Hyun Cho
Affiliation:1. Department of Pharmacology and Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea;2. Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea;3. Department of Biomedical Sciences, Seoul National University College of Medicine, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea;4. Fight Against Angiogenesis‐Related Blindness Laboratory, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea;5. College of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Republic of Korea;6. Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea;7. Department of Neurosurgery, Seoul National University Hospital, Seoul, Republic of Korea;8. Medical Research Institute, College of Medicine, Chung‐Ang University, Seoul, Republic of Korea;9. Department of Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea
Abstract:
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