Yersinia type III secretion: send in the effectors |
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| Authors: | Cornelis Guy R |
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| Affiliation: | 1.Biozentrum der Universität Basel, CH-4056 Basel, Switzerland; 2.Christian de Duve Institute of Cellular Pathology, Université Catholique de Louvain, B 1200 Brussels, Belgium |
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| Abstract: | ![]()
Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block the cells' response to infection. Understanding the molecular mechanisms of this system has provided insight into the processes of phagocytosis and inflammation. |
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| Keywords: | bacterial pathogenesis Yersinia Yops translocation type III secretion |
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