A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database |
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Authors: | José L Jiménez Björn Hegemann James RA Hutchins Jan-Michael Peters Richard Durbin |
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Affiliation: | (1) Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK;(2) Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, 1030 Vienna, Austria |
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Abstract: | mtcPTM is an online repository of human and mouse phosphosites in which data are hierarchically organized to preserve biologically
relevant experimental information, thus allowing straightforward comparisons of phosphorylation patterns found under different
conditions. The database also contains the largest available collection of atomic models of phosphorylatable proteins. Detailed
analysis of this structural dataset reveals that phosphorylation sites are found in a heterogeneous range of structural and
sequence contexts. mtcPTM is available on the web . |
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Keywords: | |
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