The 5' untranslated region of alfalfa mosaic virus RNA 1 is involved in negative-strand RNA synthesis |
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| Authors: | Vlot A Corina Bol John F |
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| Affiliation: | Institute of Biology, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands. |
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| Abstract: | ![]()
The three genomic RNAs of alfalfa mosaic virus each contain a unique 5' untranslated region (5' UTR). Replacement of the 5' UTR of RNA 1 by that of RNA 2 or 3 yielded infectious replicons. The sequence of a putative 5' stem-loop structure in RNA 1 was found to be required for negative-strand RNA synthesis. A similar putative 5' stem-loop structure is present in RNA 2 but not in RNA 3. |
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