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Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors
Authors:Johan Boström  Jonathan L Robinson  Fredrik Edfors  Rainer Tuominen  Kristel Kemper  Oscar Krijgsman  Daniel S Peeper  Jens Nielsen  Johan Hansson  Suzanne Egyhazi Brage  Mikael Altun  Mathias Uhlen  Gianluca Maddalo
Affiliation:1. Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden;2. Department of Biology and Biological Engineering, Chalmers University of Technology, G?teborg, Sweden;3. Science for Life Laboratory, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden;4. Department of Oncology‐Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden;5. Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Abstract:
Keywords:CDK2  Hsp90 and BRAF inhibitors  melanoma     MITF     proteomics
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