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Interaction of DNA with a porphyrin ligand: evidence for intercalation. |
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| Authors: | R J Fiel J C Howard E H Mark N Datta Gupta |
| Abstract: | The porphyrin photosensitizer, meso-Tetra (4-N-methylpyridyl) porphine tetraperchlorate binds to calf thymus DNA by intercalation and by external electrostatic association. This was concluded from the results of measruements involving Scatchard analysis, viscometry, thermal denaturation, and circular dichroism. |
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