Preparation and application of freeze-dried platelets |
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| Authors: | Yingyu He Yan Liu Yong Qi Shangen Zheng Lei Liu |
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| Affiliation: | 1.The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China2.Department of Transfusion Medicine, General Hospital of Central Theater Command, Wuhan, Hubei 430070, China |
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| Abstract: | Clinical platelet infusion is primarily used to prevent or stop bleeding, but can also have a role in treating infections or promoting wound healing. The demand for platelets has increased in recent years. However, as platelets can only be stored for short periods, there is a substantial loss due to the products reaching their expiry date. Platelet lyophilization is a particularly valuable and important research field. The purpose of studying the freeze-drying preservation of platelets is to realize the long-term preservation of platelets at room temperature. It is very possible to prepare qualified freeze-dried platelets. However, there are still problems that have not been solved in the process of platelet lyophilization. This review mainly summarizes research progress in the preparation and application of freeze-dried platelets. |
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| Keywords: | freeze-dried platelet pretreatment freeze-drying technology rehydration derivative product |
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