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Transformation of Salmonella typhimurium by Plasmid Deoxyribonucleic Acid |
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| Authors: | Esther M. Lederberg and Stanley N. Cohen |
| Abstract: | A modified transformation procedure that is effective for the introduction of plasmid deoxyribonucleic acid at high frequency into Salmonella typhimurium, as well as into Escherichia coli, is described. Transformed bacteria acquire a circular deoxyribonucleic acid species having the genetic and molecular characteristics of the transforming plasmid. |
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