Affiliation: | 1 Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America, 2 Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America, 3 Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan, 4 Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America, 5 Department of Chemical Engineering, University of Delaware, Newark, Delaware, United States of America, 6 6 Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America |