A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing. |
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| Authors: | W T Markiewicz, G Gr ger, R R sch, A Zebrowska, M Markiewicz, M Klotz, M Hinz, P Godzina, H Seliger |
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| Affiliation: | W T Markiewicz, G Gröger, R Rösch, A Zebrowska, M Markiewicz, M Klotz, M Hinz, P Godzina, and H Seliger |
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| Abstract: | ![]()
A new approach to the chemical synthesis of oligodeoxynucleotides bearing reporter functional groups at base residues of 3'-end nucleosides is reported. Applications of the 3'-end fluorescently labelled primers for automated DNA sequencing are shown. |
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