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Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography |
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| Authors: | D L Price A Stocks J W Griffin A Young K Peck |
| Abstract: | Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, 3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in various anatomic compartments. Quantiative analysis showed that 3H]glycine labeled a high proportion of axosomatic and axodendritic synapses which presumably act to inhibit spinal motor neurons. |
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