Dof基因家族调节植物生长发育功能的研究进展
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国家自然科学基金(31601785);


Advances in Research of the Dof Gene Family in Plant
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    摘要:

    Dof(DNA binding with one finger)蛋白是一类植物特异性转录因子,通常含有200~400个氨基酸和2个主要结构域。该家族成员的N末端为高度保守的单锌指Dof结构域,具有与DNA和蛋白质相互作用的双重功能,其C末端的氨基酸序列则较为多变,是Dof蛋白重要的特异转录调控结构域。研究表明,Dof蛋白作为转录激活物或阻遏物参与了多方面的植物生长发育过程。随着基因组测序技术的发展,已有大量的Dof基因从植物基因组数据库中鉴定出来。该文对近年来国内外有关Dof基因家族的结构特点、全基因组鉴定、蛋白互作以及生物学功能等方面的研究进展进行综述,以期为Dof转录因子的深入研究提供参考。

    Abstract:

    The DNA binding with one finger (Dof) protein is a kind of plant specific transcription factors, which usually has 200-400 amino acids and two main domains. The Nterminal of the Dof protein was highly conserved and could interact with DNA and protein. The Cterminal which has variable amino acid sequence is the specific transcriptional regulatory domain of Dof gene. Recently, it has been reported that Dof proteins are involved in the growth and development of different plants as transcriptional activators or repressors. Until now, with the rapid development of genome sequencing technology, a large number of Dof genes have been identified from different species. Here, the structural features, member identification in whole genome, interaction proteins, as well as the progress of biological function of Dof family members from different plants in recent years were summarized, and we hope this work would be helpful in the further study of Dof transcription factors.

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李 娅,丁文杰,江海燕,等.Dof基因家族调节植物生长发育功能的研究进展[J].西北植物学报,2018,38(9):1758-1766

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  • 在线发布日期: 2018-10-23
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