Endemism in the Flora of Guangxi is surveyed and analyzed. The result shows thatGuangxi is rich in endemics. 61 Senera of seed plants endemic to China are found in the region, of which 12 are indigenous. The degree of endemism of Guangxi flora is thehishest next to Yunnan which has 15 indigenous endemic genera. The 12 genera endemicto Guangxi are Heteroplexis、Brachiostemvn、Rhaphiocarpus、Buxiphyllum、Gyrogyne、Allostigma、Dayavshania、Dolicholoma、Metabriggsia、Schistolobos、Pseudochirita and Dendrocalamopsis.The flora of Guangxi is also abundant in endemic species amounting to 696 speciesand belonging to 285 genera and 105 families. They tend to be strongly tropical and subtropical in nature, and were likely to originate from the local regions.Endemism developed in the limestone regions of Guangxi shows a remarkable feature. of the 696 endemic species, 230 are exclusively distributed in the limestone regions.This phenomenon is conspicuous,in Gesneriaceae and Sect. Chrysantha Chang ofTheaceac.