Molluginaceae is a taxonomically difficult family in Caryophyllales, and its circumscription was much controversial among different systems of angiosperm classification. Based on result from a recent molecular phylogenetic study, the circumscription of Molluginaceae was well-established and 11 genera within the family were accepted, and thus a taxonomic revision of Molluginaceae in China is revised accordingly. Finally, seven species belong to five genera of Molluginaceae were accepted, and the species Hypertelis umbellata (Forssk.) Thulin is newly recorded from China. Detailed morphological description of all genera and distribution maps of all species accepted, as well a key to all of relevant species, were provided.